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High & Low Testosterone Levels: Symptoms, Signs & Side Effects

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High & Low Testosterone Levels: Symptoms, Signs & Side Effects

But if it’s just slightly low, as is more common, you’d definitely want to have symptoms,” says Bradley Anawalt, MD, chief of medicine at the University of Washington. But perhaps what’s more important is the overall trend of your testosterone level and whether you have symptoms. If you have no symptoms but are at the lower end of normal, this may well be normal for you. Two areas of the brain are involved called the hypothalamus and pituitary gland. The hypothalamus instructs the pituitary gland to release luteinising hormone (LH) which prompts the Leydig cells in the testes to produce testosterone.

However, what is considered clinically low levels of testosterone varies across guidelines, typically from 230–340 ng/dL. Your lab report should show the range that your lab uses for each test. Your doctor will also look at your results based on your age, health, and other factors. A value that isn’t in the normal range may still be normal for you. Treatment for high testosterone depends on the cause, but generally, it is a combination of lifestyle changes and medications.

The sex hormone–binding protein rises with age, so an older man may have a normal total testosterone level but still be low where it counts, in bioavailable testosterone. Instead of a single normal level for testosterone, normal men exhibit a wide range, with testosterone levels between 270 and 1,070 nanograms per deciliter (ng/dL). But, like so many biological functions, testosterone production waxes and wanes over a 24-hour cycle; production is highest at 8 a.m. For measurements to be meaningful, they should be obtained at a standard time, usually first thing in the morning. Both males and females can experience health problems if their testosterone levels are out of the normal range.

If you have symptoms of testosterone deficiency, by all means, check your levels and consult your doctor. Otherwise, be reassured that testosterone levels can gradually decline as you get older. You can check your testosterone levels at home with a home Testosterone Blood Test. Or, for a more comprehensive check of your hormones, a Male Hormone Test looks at a broader range of male hormones. One study that looked at over 50,000 male blood samples found there was only a very gradual decline in testosterone levels from age 30, but this decline was more noticeable from age 80.

Because hormone levels change rapidly during puberty and development can occur at different ages for different people, the Tanner scale is a more accurate way to judge changes during puberty than using age. In males, the testes produce testosterone, while the ovaries produce testosterone in females. The adrenal glands also produce small amounts of testosterone in both sexes.

More than a third of men over age 45 may have reduced levels of testosterone than might be considered normal (though, as mentioned, defining optimal levels of testosterone is tricky and somewhat controversial). Among women, perhaps the most common cause of a high testosterone level is polycystic ovary syndrome (PCOS). For both an adolescent and adult male, 400 ng/dl testosterone is within a healthy range. However, this amount of testosterone is high for a male child or females.

The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects. Any issue with your testicles, hypothalamus or pituitary gland can cause low testosterone (male hypogonadism). The most common type of testosterone test is a total testosterone test, which measures the free testosterone in your blood and testosterone attached to proteins. In people who are premenopausal, testosterone is made mainly in the ovaries.

Finally, increasing levels of testosterone through a negative feedback loop act on the hypothalamus and pituitary to inhibit the release of GnRH and FSH/LH, respectively. Conditions that affect how your hypothalamus and/or pituitary gland cause secondary hypogonadism. This is known as hypogonadotropic hypogonadism because there are low levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Those low levels cause decreased testosterone and sperm production. Low testosterone (male hypogonadism) is a condition in which your testicles don’t produce enough testosterone. It has several possible causes, including conditions or injuries affecting your testicles, pituitary gland or hypothalamus. The designation of “healthy range” for testosterone booster ratings levels depends on age and laboratory assay.

Although the Endocrine Society and a multidisciplinary Canadian panel recommend annual PSA and digital rectal examination screening in men 40 years and older,9,11 the U.S. Total testosterone levels alone are not enough to diagnose any health condition. Test results are interpreted in the context of your specific health situation. Your doctor may recommend repeat testing or additional tests to learn more about what may be causing your symptoms and/or the change in your testosterone level. Testosterone tests can also monitor the health of transgender men who were assigned female at birth but identify as male.

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